Acetyl chloride → HCID 21498237, compound

HRID 1730493Notes

Reaction equation

HRID 1730493 reaction equation
[C:1](Cl)(=O)[CH3:2].[Br:5][C:6]1[CH:15]=[CH:14][CH:13]=[C:12]2[C:7]=1[CH:8]=[CH:9][N:10]=[C:11]2[NH:16][NH2:17].CC1N2C=CC3C(C2=NN=1)=CC=CC=3Cl>>[CH3:1][C:2]1[N:10]2[CH:9]=[CH:8][C:7]3[C:12]([C:11]2=[N:16][N:17]=1)=[CH:13][CH:14]=[CH:15][C:6]=3[Br:5]

Participants

4

Reactant 3

HCID 6367Acetyl chlorideHCID 21498222HCID 21498222, compoundHCID 21498249HCID 21498249, compound

Product 1

HCID 21498237HCID 21498237, compound

Procedure

3-Methyl-7-bromo-s-triazolo-[3,4-a]-isoquinoline was prepared from acetyl chloride and 5-bromo-1-hydrazinoisoquinoline by a method generally similarto that described below for the preparation of 3-methyl-7-chloro-s-triazolo-[3,4-a]-isoquinoline. Yield, 78.5%; m.p. 203°-204°C.

Workup

  1. customYield

Sources & evidence

ORD record
ord-85b389b8e63c47a7b2007fc7c4fa078e
Source dataset
uspto-grants-1976_11
Patent number
US03992539

Reaction notes

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