HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene → HCID 21498285, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene | HCID 241 | — |
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | Pyrrolidine | HCID 31268 | — |
| Reactant | 1-Benzyl-3-methyl-4-piperidone | HCID 560965 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 21498285 | HCID 21498285 | — |
Reaction Steps
A mixture of 1-benzyl-3-methyl-4-piperidone (91 g), pyrrolidine (35.6 g), p-toluenesulphonic acid (0.5 g) and dry benzene (400 ml) was heated under reflux under a Dean and Stark trap until separation of water was complete.The solvent was removed on a rotary evaporator and the residue distilled togive 95 g of a colourless liquid boiling at 144°-6° C (0.01 mm).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03992544 |
| Source dataset | uspto-grants-1976_11 |
| ORD ID | ord-c008a788e2df4082b4b161873031806b |
| Source note | uspto-grants-1976_11 |