Acetic Acid → HCID 21498287, compound

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A mixture of 1,5-dibenzyl-4,5,6,7-tetrahydro-7-methyl-2-phenyl-1H-pyrrolo[3,2-c]pyridine (2 g), formaldehyde (1 ml 40% aqueous solution) and dimethylamine hydrochloride (1 g) in glacial acetic acid (20 ml) was kept at room temperature for 3 days and then poured into water (150 ml). The mixture was extracted with ether (2 × 100 ml), the ether extracts washed with saturated sodium carbonate solution (3 × 100 ml), dried over magnesium sulphate and evaporated. Trituration of the resulting oil with ether gave the title compound as white needles. 0.82 g M.pt. 126° C(Found: C, 79.8; H, 7.1; N, 6.0. C31H30N2O2 requires: C, 80.1; H, 6.9; N, 6.0.

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