4-Chloroaniline → HCID 21498255, compound

HRID 1730515Notes

Reaction equation

HRID 1730515 reaction equation
[CH2:1]([N:8]1[CH2:13][CH:12]([CH2:14][C:15]([C:17]2[CH:22]=[CH:21][C:20]([Cl:23])=[CH:19][CH:18]=2)=O)[C:11](=O)[CH:10]([CH3:25])[CH2:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Cl:26][C:27]1[CH:33]=[CH:32][C:30]([NH2:31])=[CH:29][CH:28]=1>>[CH2:1]([N:8]1[CH2:9][CH:10]([CH3:25])[C:11]2[N:31]([C:30]3[CH:32]=[CH:33][C:27]([Cl:26])=[CH:28][CH:29]=3)[C:15]([C:17]3[CH:22]=[CH:21][C:20]([Cl:23])=[CH:19][CH:18]=3)=[CH:14][C:12]=2[CH2:13]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 78124-ChloroanilineHCID 21498261HCID 21498261, compound

Product 1

HCID 21498255HCID 21498255, compound

Procedure

Using a procedure analogous to Example 3, 1-benzyl-3-methyl-5-(p-chlorophenacyl)-4-piperidone may be reacted with p-chloroaniline to give the title compound.

Sources & evidence

ORD record
ord-ef6d71c1f0fe4f1392467df5930d2bf9
Source dataset
uspto-grants-1976_11
Patent number
US03992544

Reaction notes

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