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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1730522Generated: November 2, 2026

4-Methylbenzaldehyde → HCID 12308275, compound

https://huagongshe.com/reaction/1730522

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzaldehydeHCID 7725—
Reactantbeta-Aminobeta-ethoxyacrylic acid ethyl esterHCID 278451—
SolventEthyl AcetateHCID 8857—
ProductHCID 12308275HCID 1230827547%

Reaction Steps

Upon heating a solution of 6 g of 4-methylbenzaldehyde and 15.9 g of 3-amino-3-ethoxyacrylic acid ethyl ester in 50 ml of alcohol for 6 hours, 2-amino-4-(4-methylphenyl)-6-ethoxy-4,5-dihydropyridine-3,5-dicarboxylic acid diethyl ester of melting point 119° C (ethyl acetate/petroleumether) is obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03992545
Source datasetuspto-grants-1976_11
ORD IDord-0f11a9eef9c249548615d5ae69f1776f
Source noteuspto-grants-1976_11