2-Methoxyaniline → HCID 54695954, compound

HRID 1730539Notes

Reaction equation

HRID 1730539 reaction equation
CO[C:3]([C:5]1[N:6]([CH3:22])[S:7](=[O:21])(=[O:20])[C:8]2[C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[CH:13]=[CH:12][C:9]=2[C:10]=1[OH:11])=[O:4].[CH3:23][O:24][C:25]1[CH:31]=[CH:30][CH:29]=[CH:28][C:26]=1[NH2:27]>>[OH:11][C:10]1[C:9]2[CH:12]=[CH:13][C:14]3[C:19]([C:8]=2[S:7](=[O:21])(=[O:20])[N:6]([CH3:22])[C:5]=1[C:3]([NH:27][C:26]1[CH:28]=[CH:29][CH:30]=[CH:31][C:25]=1[O:24][CH3:23])=[O:4])=[CH:18][CH:17]=[CH:16][CH:15]=3

Participants

3

Reactant 2

HCID 70002-MethoxyanilineHCID 546906514-hydroxy-2-methyl-2H-naphtho[2,1-e]-1,2-thiazine-3-carboxylic acid methylester-1,1-dioxide

Product 1

HCID 54695954HCID 54695954, compoundYield 31%

Procedure

4-Hydroxy-N-(2-methoxyphenyl)-2-methyl-2H-naphtho[2,1-e]-1,2-thiazine-3-carboxamide-1,1-dioxide was prepared analogous to Example 1 from 4-hydroxy-2-methyl-2H-naphtho[2,1-e]-1,2-thiazine-3-carboxylic acid methylester-1,1-dioxide and 2-methyoxy-aniline. Yield: 31% of theory; m.p. 198°-200° C (from ethylene chloride/petroleum ether).

Sources & evidence

ORD record
ord-c3c531949bd54b74b4e554114c386d26
Source dataset
uspto-grants-1976_11
Patent number
US03992535

Reaction notes

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