HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Amino-5-methylisoxazole → 4-hydroxy-2-methyl-N-(2-thiazolyl)-2H-naphtho [2,1-e]-1,2-thiazine-3-carboxamide-1,1-dioxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Amino-5-methylisoxazole | HCID 66172 | — |
| Reactant | 2-methyl-4-(1-pyrrolidyl)-2H-naphtho[2,1-e]-1,2-thiazine-3-carboxylic acidchloride-1,1-dioxide | HCID 21498111 | — |
| Reactant | 4-Hydroxy-2-methyl-N-(5-methyl-3-isoxazolyl)-2H-naphtho [2,1-e]-1,2-thiazine-3-carboxamide-1,1-dioxide | HCID 54695935 | — |
| Product | 4-hydroxy-2-methyl-N-(2-thiazolyl)-2H-naphtho [2,1-e]-1,2-thiazine-3-carboxamide-1,1-dioxide | HCID 54718410 | — |
Reaction Steps
4-Hydroxy-2-methyl-N-(5-methyl-3-isoxazolyl)-2H-naphtho [2,1-e]-1,2-thiazine-3-carboxamide-1,1-dioxide, m.p. 235° C, from 2-methyl-4-(1-pyrrolidyl)-2H-naphtho[2,1-e]-1,2-thiazine- 3-carboxylic acid chloride-1,1-dioxide and 3-amino-5-methylisoxazole.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03992535 |
| Source dataset | uspto-grants-1976_11 |
| ORD ID | ord-ce1bb6f113c5472eb631ecd18c58f6d0 |
| Source note | uspto-grants-1976_11 |