4-(Chloromethyl)pyridine → 4-({2-[2-(5-Nitrofuran-2-yl)ethenyl]-1H-imidazol-1-yl}methyl)pyridine

HRID 1730622Notes

Reaction equation

HRID 1730622 reaction equation
[N:1]1[CH:6]=[CH:5][C:4]([CH2:7]Cl)=[CH:3][CH:2]=1.[N+:9]([C:12]1[O:16][C:15]([CH:17]=[CH:18][C:19]2[NH:20][CH:21]=[CH:22][N:23]=2)=[CH:14][CH:13]=1)([O-:11])=[O:10]>>[N:1]1[CH:6]=[CH:5][C:4]([CH2:7][N:23]2[CH:22]=[CH:21][N:20]=[C:19]2[CH:18]=[CH:17][C:15]2[O:16][C:12]([N+:9]([O-:11])=[O:10])=[CH:13][CH:14]=2)=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 745714-(Chloromethyl)pyridineHCID 286751HCID 286751, compound

Product 1

HCID 541492574-({2-[2-(5-Nitrofuran-2-yl)ethenyl]-1H-imidazol-1-yl}methyl)pyridine

Procedure

Using the same general procedure of Example 1, the captioned compound was prepared using 4-picolyl chloride and 2-[2-(5-nitro-2-furyl)vinyl]imidazole. Recrystallization from ethanol-water gave an orange solid product melted 130°-131°.

Workup

  1. customthe captioned compound was prepared
  2. customRecrystallization from ethanol-water
  3. customgave an orange solid product
  4. custommelted 130°-131°

Sources & evidence

ORD record
ord-639263b8abc64996a70565b256395211
Source dataset
uspto-grants-1976_11
Patent number
US03993643

Reaction notes

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