Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 4-Nitroaniline | HCID 7475 | — |
| Reactant | 4,4A,5,5a,6,6a-hexahydro-1H-4,6-ethenocyclopropa[f]isobenzofuran-1,3(3aH)-dione | HCID 260032 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 2829574 | HCID 2829574 | — |
Reaction Steps
250 g of tricyclo-[3.2.2.02.4 ]-non-8-ene-6,7-dicarboxylic acid anhydride (prepared from cycloheptatriene and maleic acid anhydride, K. Alder, Ber. 86, 1528-39 (1953)) and 200 g of 4-nitroaniline are refluxed in 1500 ml of glacial acetic acid for 3 hours. The reaction mixture cooled to 60° C is poured into 2000 ml of hot water, whereupon the crude product precipitates. After cooling, the crude product is filtered off, dried, and recrystallised from ethyl acetate; M.P. 210°-212° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US03993662 |
|---|
| Source dataset | uspto-grants-1976_11 |
|---|
| ORD ID | ord-46dfa1e78fbf46af9e465327256b6a8f |
|---|
| Source note | uspto-grants-1976_11 |
|---|
