Hydrogen Peroxide → HCID 149148934, compound

Participants

Reaction Steps

2.3 ml of H2O2 (30%) are added dropwise to a solution of 8.9 g of N-(2-butyramido-4-phenylthiophenyl)-N',N"-bis-methoxycarbonyl-guanidine (m.p. 155° C, Example 4) in 1.4 1 of acetic acid anhydride. After 10 hours the batch is concentrated in vacuo, a mixture of ethyl acetate and petroleum ether added to the residue and filtered. 8.5 g of N-(2-butyramido-4-phenylsulphinylphenyl)-N,N'-bis-methoxycarbonyl-guanidine are obtained with a m.p. of 186° C (decomp.), (redissolved from methanol/ethyl acetate). The mass spectrum shows a mol peak of 460.

Provenance & Evidence