Chloroform → HCID 70360863, compound

HRID 1730699Notes

Reaction equation

HRID 1730699 reaction equation
[O:1]([CH2:8][C:9]([NH:11][CH:12]1[C:25](=[O:26])[N:14]2[CH:15]([C:21]([O:23][CH3:24])=[O:22])[C:16](C)([CH2:18][Br:19])[S:17][C@H:13]12)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH:27](Cl)(Cl)Cl>>[O:1]([CH2:8][C:9]([NH:11][CH:12]1[C:25](=[O:26])[N:14]2[CH:15]([C:21]([O:23][CH3:24])=[O:22])[C:18]([Br:19])([CH3:27])[CH2:16][S:17][C@H:13]12)=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 6212ChloroformHCID 70360981HCID 70360981, compound

Product 1

HCID 70360863HCID 70360863, compound

Procedure

Methyl 6-(2-phenoxyacetamido)-2-methyl-2-bromomethylpenam-3-carboxylate (350 mg.) was dissolved in chloroform (10 cc), and then the mixture was allowed to stand for 4 days and purified by chromatography of silica gel to give an amorphous material (200 mg.) of methyl 7-(2-phenoxyacetamido)-3-bromo-3-methylcepham-4-carboxylate.

Workup

  1. custompurified by chromatography of silica gel

Sources & evidence

ORD record
ord-3370fb9060314ac6b182a5adad3fb4ad
Source dataset
uspto-grants-1976_11
Patent number
US03993646

Reaction notes

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