Potassium Hydroxide → HCID 20348753, compound

Participants

Reaction Steps

220 gm of the methyl ester obtained in Example B were hydrolized with 58.2 gm of potassium hydroxide in 900 ml of ethanol by boiling for 1 hour. Subsequently, the mixture was diluted with 1800 ml of water, the neutral components were extracted with ether, and the free acid was precipitated from the alkaline phase. By extraction with ether, and washing, drying and evaporating the ethereal extract, the reaction product was isolated. Yield: 130 gm (62% of theory); oil, Rf -value: 0.7 (cyclohexane-ethyl acetate = 1:1 on silicagel-polygram-plates).

Provenance & Evidence