Sodium Hydroxide → HCID 21496150, compound

HRID 1730762Notes

Reaction equation

HRID 1730762 reaction equation
[Cl:1][C:2]1[CH:20]=[CH:19][CH:18]=[CH:17][C:3]=1[C:4]([C:6]1[CH:15]=[C:14]([Cl:16])[CH:13]=[CH:12][C:7]=1[NH:8][C:9](=[O:11])[CH3:10])=O.[OH-].[Na+]>>[Cl:16][C:14]1[CH:15]=[C:6]2[C:7](=[CH:12][CH:13]=1)[NH:8][C:9](=[O:11])[CH:10]=[C:4]2[C:3]1[CH:17]=[CH:18][CH:19]=[CH:20][C:2]=1[Cl:1]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 540625N-[4-Chloro-2-(2-chlorobenzoyl)phenyl]acetamide

Product 1

HCID 21496150HCID 21496150, compound

Procedure

In the manner given in Preparation 2, 2'-(o-chlorobenzoyl)-4'-chloroacetanilide was reacted with sodium hydroxide to give 6-chloro-4-(o-chlorophenyl)-2(1H)-quinolone.

Sources & evidence

ORD record
ord-03e76b5daca347e7b9c902e8d9a1a957
Source dataset
uspto-grants-1976_11
Patent number
US03993660

Reaction notes

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