2(5H)-Thiazolone, 4-amino- → HCID 178509023, compound

HRID 1730781Notes

Reaction equation

HRID 1730781 reaction equation
[NH:1]=[C:2]1[CH2:6][S:5][C:4](=[O:7])[NH:3]1.[NH:8]=[C:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:11](=N)[NH:10]1>CO>[NH:8]=[C:9]1[C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[C:11](=[C:6]2[S:5][C:4](=[O:7])[NH:3][C:2]2=[NH:1])[NH:10]1

Participants

4

Reactant 2

HCID 1373471612(5H)-Thiazolone, 4-amino-HCID 178508669HCID 178508669, compound

Product 1

HCID 178509023HCID 178509023, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of 3.5 parts of 4-imino-2-thiazolidinone, 4.4 parts of 1,3-diiminoisoindoline and 100 parts of methanol was stirred under an atmosphere of nitrogen at room temperature for three hours and then at reflux temperature for 2 hours. The reaction mixture was cooled to 25° C and the solid therein was collected by filtration, washed with fresh methanol and dried in varuo at 50° C to obtain 5.4 parts of 1-imino-3-(2-oxo-4-imino-5-thiazolidinylidene)isoindoline as a yellow powder melting at 346°-348° C (dec).

Workup

  1. temperatureat reflux temperature for 2 hours
  2. temperatureThe reaction mixture was cooled to 25° C
  3. filtrationthe solid therein was collected by filtration
  4. washwashed with fresh methanol
  5. customdried in varuo at 50° C

Sources & evidence

ORD record
ord-509dc101c02d44e7aacacf6a711b4f27
Source dataset
uspto-grants-1976_11
Patent number
US03993658

Reaction notes

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