反应详情

A mixture of 3.5 parts of 4-imino-2-thiazolidinone, 4.4 parts of 1,3-diiminoisoindoline and 100 parts of methanol was stirred under an atmosphere of nitrogen at room temperature for three hours and then at reflux temperature for 2 hours. The reaction mixture was cooled to 25° C and the solid therein was collected by filtration, washed with fresh methanol and dried in varuo at 50° C to obtain 5.4 parts of 1-imino-3-(2-oxo-4-imino-5-thiazolidinylidene)isoindoline as a yellow powder melting at 346°-348° C (dec).

1. temperatureat reflux temperature for 2 hours
2. temperatureThe reaction mixture was cooled to 25° C
3. filtrationthe solid therein was collected by filtration
4. washwashed with fresh methanol
5. customdried in varuo at 50° C