2-Pyrrolidino-4-imino-2-thiazoline hydrochloride → HCID 178508575, compound

HRID 1730795Notes

Reaction equation

HRID 1730795 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]2[CH2:16][CH2:15][CH:14]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[C:13]3[C:12](=[NH:23])[NH:11][C:10](=N)[C:9]2=3)=[CH:4][CH:3]=1.Cl.[N:26]1([C:31]2[S:32][CH2:33][C:34](=[NH:36])[N:35]=2)[CH2:30][CH2:29][CH2:28][CH2:27]1.N=C1C2CCCCC=2C(=N)N1.Cl.N=C1NC(=N)CS1>>[NH:23]=[C:12]1[C:13]2[CH:14]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[CH2:15][CH2:16][CH:8]([C:5]3[CH:4]=[CH:3][C:2]([Br:1])=[CH:7][CH:6]=3)[C:9]=2[C:10](=[C:33]2[S:32][C:31]([N:26]3[CH2:30][CH2:29][CH2:28][CH2:27]3)=[N:35][C:34]2=[NH:36])[NH:11]1

Participants

5

Reactant 4

HCID 162452972-Pyrrolidino-4-imino-2-thiazoline hydrochlorideHCID 176526843HCID 176526843, compoundHCID 178479111HCID 178479111, compoundHCID 178508595HCID 178508595, compound

Product 1

HCID 178508575HCID 178508575, compound

Procedure

When equivalent amounts of 4-(p-bromophenyl)-7-phenyl-4,5,6,7-tetrahydro-1,3-diiminoisoindoline and 2-pyrrolidino-4-imino-2-thiazoline hydrochloride are substituted for the 4,5,6,7-tetrahydro-1,3-diiminoisoindoline and 2,4-diiminothiazolidine hydrochloride respectively, in the procedure described in Example 10, part A above, there is obtained as the product 1-imino-4-(p-bromophenyl)-7-phenyl-4,5,6,7-tetrahydro-3-(2-pyrrolidino-4-imino-2-thiazolin-5-ylidene)isoindoline.

Sources & evidence

ORD record
ord-83e5392e74c34946aab51a39023dde33
Source dataset
uspto-grants-1976_11
Patent number
US03993658

Reaction notes

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