Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | 3-Phenylprop-2-enoyl chloride | HCID 66023 | — |
| Reactant | 4-(3-(Dimethylamino)propoxy)aniline | HCID 10058469 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | HCID 131710540 | HCID 131710540 | 87.9% |
Reaction Steps
A solution of 16.6g of cinnamoyl chloride in 125 ml of chloroform is cooled to 15° C and treated dropwise with a solution of 19.4g of 4-[3-(dimethylamino)propoxy]benzenamine in 75 ml of chloroform, keeping the temperature between 15° and 20° C. After stirring for 1 hour, the mixture is heated at reflux for 1 hour, cooled to 25° C and treated with 300 ml of ether to yield 31.6g of material, melting point 253°-257° C, dec.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US03994900 |
|---|
| Source dataset | uspto-grants-1976_11 |
|---|
| ORD ID | ord-7bfbc2f32c2a437384de9314975b53e5 |
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| Source note | uspto-grants-1976_11 |
|---|
