N-(3-chloropropyl)piperidine hydrochloride → HCID 68139355, compound

HRID 1730932Notes

Reaction equation

HRID 1730932 reaction equation
[C:1]1([C:7]2[C:15]3[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=3)[NH:9][N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Cl.[N:17]1([CH2:23][CH2:24][CH2:25][Cl:26])[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]1>>[ClH:26].[N:17]1([CH:23]([C:14]2[CH:13]=[CH:12][CH:11]=[C:10]3[C:15]=2[C:7]([C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)=[N:8][NH:9]3)[CH2:24][CH3:25])[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]1

Participants

3

Reactant 2

HCID 79624N-(3-chloropropyl)piperidine hydrochlorideHCID 3003853-phenyl-1H-indazole

Product 1

HCID 68139355HCID 68139355, compoundYield 74.5%

Procedure

By the procedure similar to that described in Example 1, 3-phenylindazole (3.88 g) and piperidinopropyl chloride hydrochloride (5.94 g) were treated to obtain 5.3 g of 1-piperidinopropyl-3-phenylindazole hydrochloride (m.p. 201°-202° C).

Workup

  1. additionwere treated

Sources & evidence

ORD record
ord-526684922df74f66b22ecaedd66a2e45
Source dataset
uspto-grants-1976_11
Patent number
US03994890

Reaction notes

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