HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperidine → HCID 21563703, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 4-ethoxy-2-hydroxybenzaldehyde | HCID 2396511 | — |
| Reactant | 3-Phenyl-1,2,4-oxadiazole-5-acetic acid | HCID 7017713 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 21563703 | HCID 21563703 | — |
Reaction Steps
5 parts of 2-hydroxy-4-ethoxy benzaldehyde and 7 parts of the ethyl ester of 3-phenyl-1,2,4-oxadiazole-5-acetic acid are dissolved in 80 parts of ethanol, then 0.3 part of piperidine is added. The mixture is heated under reflux for one hour, then the precipitate obtained after cooling is filtered. 8 parts of 7-ethoxy-3-(3-phenyl 1,2,4-oxadiazol-5-yl) coumarin are obtained which melts at 229° C. after crystallization in dioxane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03994907 |
| Source dataset | uspto-grants-1976_11 |
| ORD ID | ord-fcb2dcfb1eaa4cd0bca82f1520d1b6b4 |
| Source note | uspto-grants-1976_11 |