2-Amino-4-methylpyridine → 1,2-Diphenyl-3,5-dioxo-4-n-butylpyrazolidine 2-amino-4-methyl-pyridine

Participants

Reaction Steps

30.8 g (0.1 mol) of 1,2-diphenyl-3,5-dioxo-4-n-butyl-pyrazolidine are introduced with agitation into a 500 cc flask and mixed with 150 ml of acetone until complete dissolution. 10.8 g (0.1 mol) of 2-amino-4-methylpyridine which have previously been dissolved in 100 cc of acetone are then added and the mixture is boiled for 30 minutes. It is filtered cold, and 39 g of a product having a melting point of 121°-2° C are crystallized out.

Provenance & Evidence