HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Chloropropyl)-4-phenylpiperidine → 3-[3-(4-Phenyl-1-Piperidyl)Propyl]-5-Phenyl-5-(2-Pyridyl)Hydantoin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Chloropropyl)-4-phenylpiperidine | HCID 203689 | — |
| Reactant | Mls002667559 | HCID 243331 | — |
| Reactant | 3-[2-(4-Phenyl-1-piperidyl)ethyl]-5-phenyl-5-(2-pyridyl)-hydantoin | HCID 21395252 | — |
| Reactant | 1-(Chloromethyl)-4-phenyl-piperidine | HCID 21395258 | — |
| Product | 3-[3-(4-Phenyl-1-Piperidyl)Propyl]-5-Phenyl-5-(2-Pyridyl)Hydantoin | HCID 21395246 | — |
Reaction Steps
Substitution of 1-(2-chloroethyl)-4-phenyl-piperidine or 1-(chloromethyl)-4-phenyl-piperidine for 1-(3-chloropropyl)-4-phenyl-piperidine in the above example respectively yields: 3-[2-(4-phenyl-1-piperidyl)ethyl]-5-phenyl-5-(2-pyridyl)-hydantoin and 3-[(4-phenyl)-1-piperidyl)methyl]-5-phenyl-5-(2-pyridyl)-hydantoin.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03994904 |
| Source dataset | uspto-grants-1976_11 |
| ORD ID | ord-cec79c31eac147ba915d50371cad3e07 |
| Source note | uspto-grants-1976_11 |