2-Benzoylbenzoic Acid → HCID 21494580, compound

HRID 1730980Notes

Reaction equation

HRID 1730980 reaction equation
[C:1]([C:9]1[CH:17]=[CH:16][CH:15]=[CH:14][C:10]=1[C:11]([OH:13])=O)(=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:18][CH:19]([CH:21]([NH2:23])[CH3:22])[CH3:20]>C1(C)C=CC=CC=1>[CH3:20][CH:19]1[CH:21]([CH3:22])[N:23]2[C:11](=[O:13])[C:10]3[C:9]([C:1]2([C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)[NH:18]1)=[CH:17][CH:16]=[CH:15][CH:14]=3

Participants

4

Reactant 2

HCID 68132-Benzoylbenzoic AcidHCID 1363622,3-Butanediamine

Product 1

HCID 21494580HCID 21494580, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Condense o-benzoylbenzoic acid (22 g.) and 2,3-diaminobutane in toluene (400 ml.) by the procedure of Example 1 to obtain 2,3-dimethyl-9b-phenyl-1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoindol-5-one, m.p. 162°-4° C. (elemental analysis confirms the empirical formula C18H18N2O) and reduce with lithium aluminum hydride as described in Example 1 to obtain 3,4-dimethyl-1,2,3,4,5,6-hexahydro-1-phenyl-2,5-benzodiazocine.

Sources & evidence

ORD record
ord-15f3295bef7943d281f2a09d6fd5d14d
Source dataset
uspto-grants-1976_11
Patent number
US03994920

Reaction notes

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