反应详情

Condense o-(2-thienoyl)benzoic acid with ethylenediamine by the procedure of Example 1 to obtain 9b-(2-thienyl)-1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoindol-5-one and reduce with lithium aluminum hydride as described in Example 1 to obtain 1,2,3,4,5,6-hexahydro-1-(2-thienyl)-2,5-benzodiazocine, m.p. 148° C. The dihydrochloride melts at 241° C.