Ethylenediamine → HCID 12205305, compound

HRID 1730984Notes

Reaction equation

HRID 1730984 reaction equation
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]([C:8]1[CH:16]=[CH:15][CH:14]=[CH:13][C:9]=1[C:10]([OH:12])=O)=O.[CH2:17]([NH2:20])[CH2:18][NH2:19]>>[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6]12[NH:20][CH2:17][CH2:18][N:19]1[C:10](=[O:12])[C:9]1[C:8]2=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

3

Reactant 2

HCID 3301EthylenediamineHCID 2826542-(2-Thienylcarbonyl)benzoic acid

Product 1

HCID 12205305HCID 12205305, compound

Procedure

Condense o-(2-thienoyl)benzoic acid with ethylenediamine by the procedure of Example 1 to obtain 9b-(2-thienyl)-1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoindol-5-one and reduce with lithium aluminum hydride as described in Example 1 to obtain 1,2,3,4,5,6-hexahydro-1-(2-thienyl)-2,5-benzodiazocine, m.p. 148° C. The dihydrochloride melts at 241° C.

Sources & evidence

ORD record
ord-28603cac5f1b427982de7580271ecbd3
Source dataset
uspto-grants-1976_11
Patent number
US03994920

Reaction notes

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