Cyclohexanol → 1-Aminoanthraquinone

Participants

Reaction Conditions

Reaction Steps

3 Grams of a Raney nickel catalyst and 100 grams of a 20% aqueous sodium hydroxide solution were added to a mixture of 128 grams of 5-nitrotetrahydroanthraquinone and 1,700 grams of cyclohexanol, into which was fed hydrogen while agitating at 100° C. for having hydrogen absorbed in the starting 5-nitro compound in an amount of 2 mols per mol of the 5-nitro compound. After completion of hydrogenation, the catalyst was separated by filtration and air was passed into the resultant filtrate at 30° C. for 1 hour. The resultant solution was cooled to 10° C. to precipitate crystals, which were then separated by filtration, washed with water and dried to obtain 92 grams of 1-aminoanthraquinone having a purity of 98.2%.

Provenance & Evidence