反应详情

A solution of 23.4 g (0.2 mol.) of t-butyl carbamate [Org. Syn., 48, 32 (1968); U.S. 3,072,710] and 32.2 g. (0.25 mol.) of n-butyl glyoxylate (Org. Syn. Col. Vol. 4, 124) in 150 ml. of acetic anhydride was refluxed for 1.25 hours. The reaction mixture was then cooled, the solvent was removed in vacuo and the residue was molecularly distilled at 130°/.05 mm. to give the title compound.

1. temperatureThe reaction mixture was then cooled
2. customthe solvent was removed in vacuo
3. distillationthe residue was molecularly distilled at 130°/.05 mm