Perchloric Acid → tert-Butyl {[(E)-{1-(2-amino-1,3-thiazol-4-yl)-2-[(1,3-benzothiazol-2-yl)sulfanyl]-2-oxoethylidene}amino]oxy}acetate

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Reaction Steps

After the flask is weighed (total weight yield); 201 g.), 183.6 g. of the reaction mixture are stripped under reduced pressure (up to about 150° C. at 0.5-mm. Hg.) to give 96.2 g. of oligomer which corresponds to a weight yield of 52.4%. Analysis of the unstripped reaction mix by vapor phase chromatography and titration of the stripped oligomer using a standard perchloric acid solution in acetic acid gives the following final composition: Lauryl acrylate: tetradecene-1: BAEM 70.3:25.2:4.5 by weight. Kjeldahl nitrogen analysis gives a value of 0.39% N corresponding to 5.5% by weight of BAEM in the oligomer. Elemental analysis:

Provenance & Evidence