4-Chloro-2-(trifluoromethyl)pyrimidine → 4-[4-(2-Chloro-pyridin-4-ylethynyl)-2-methyl-imidazol-1-yl]-2-trifluoromethyl-pyrimidine

HRID 173106Notes

Reaction equation

HRID 173106 reaction equation
[Cl:16][c:17]1[n:18][c:19]([C:23]([F:24])([F:25])[F:26])[n:20][cH:21][cH:22]1.[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([C:8]#[C:9][c:10]2[n:11][c:12]([CH3:15])[nH:13][cH:14]2)[cH:7]1>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]([C:8]#[C:9][c:10]2[n:11][c:12]([CH3:15])[n:13](-[c:17]3[n:18][c:19]([C:23]([F:24])([F:25])[F:26])[n:20][cH:21][cH:22]3)[cH:14]2)[cH:7]1

Participants

3

Reactant 2

HCID 152943694-Chloro-2-(trifluoromethyl)pyrimidineHCID 178418879HCID 178418879, compound

Product 1

HCID 117400094-[4-(2-Chloro-pyridin-4-ylethynyl)-2-methyl-imidazol-1-yl]-2-trifluoromethyl-pyrimidine

Sources & evidence

ORD record
ord-2933cbffc6eb464a82df83a0e0c4f4c1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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