反应详情

In 60 ml of chloroform there was dissolved 5.4 g of 4-benzyloxy-3-nitroacetophenone and after adding dropwise to the solution a mixture of 3.2 g of bromine and 5 ml. of chloroform, with stirring, the mixture was further stirred for 30 minutes. The reaction product was concentrated under a reduced pressure and the crystalline residue thus obtained was washed with 20 ml. of benzene and dried to give 5.5 g of 4-benzyloxy-3-nitro-α-bromoacetophenone melting at 135°-136° C.

1. additionafter adding dropwise to the solution
2. concentrationThe reaction product was concentrated under a reduced pressure
3. customthe crystalline residue thus obtained
4. washwas washed with 20 ml
5. dry with materialof benzene and dried