Hydrazine → HCID 21494729, compound

HRID 1731107Notes

Reaction equation

HRID 1731107 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8](=O)[C:9]1[CH:14]=[C:13]([N+:15]([O-:17])=[O:16])[CH:12]=[CH:11][C:10]=1[N:18]1[C:22]([CH2:23][N:24]2C(=O)C3=CC=CC=C3C2=O)=[N:21][N:20]=[C:19]1[CH2:35][CH2:36][N:37]([CH3:39])[CH3:38].NN>C(O)C>[CH3:39][N:37]([CH3:38])[CH2:36][CH2:35][C:19]1[N:18]2[C:10]3[CH:11]=[CH:12][C:13]([N+:15]([O-:17])=[O:16])=[CH:14][C:9]=3[C:8]([C:3]3[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=3[Cl:1])=[N:24][CH2:23][C:22]2=[N:21][N:20]=1

Participants

4

Reactant 2

HCID 9321HydrazineHCID 21494772HCID 21494772, compound

Product 1

HCID 21494729HCID 21494729, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In the manner given in Example 1C, 2'-chloro-5-nitro- 2-[3-[2-(dimethylamino)ethyl]-5-(phthalimidomethyl)-4H-1,2,4-triazol-4-yl]benzophenone in ethanol is refluxed with hydrazine to give 1-[2-(dimethylamino)ethyl]-8-nitro-6-(o-chlorophenyl)-4H-s-triazolo[4,3-a][1,4]benzodiazepine. This compound is converted to its hydrochloride by treating it with ethereal hydrogen chloride.

Sources & evidence

ORD record
ord-0ffaa3004c8d4e56bca5de108ed8aa10
Source dataset
uspto-grants-1976_11
Patent number
US03994940

Reaction notes

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