Water → HCID 21495287, compound

Participants

Reaction Steps

The amide, N,N,1-trimethyl-1,3,4,9-tetrahydroindeno[2,1-c]thiopyran-1-acetamide (2.7 g), described in Example 196, in anhydrous ether (200 ml) is added dropwise to a stirred suspension of lithium alumimum hydride (1.0 g) in 100 ml of anhydrous ether. The mixture is stirred at room temperature for 30 min. Excess hydride is decomposed with water (4 ml). The mixture is filtered. The filtrate is dried (MgSO4) and concentrated to give the title compound, nmr (CDCl3), 1.45 (s, 3H), 3.50 (m, 2H), 7.32 (m, 4H).

Provenance & Evidence