Thionyl Chloride → HCID 15935408, compound

HRID 1731172Notes

Reaction equation

HRID 1731172 reaction equation
[C:1]([C:9]1[CH:10]=[C:11]([CH2:15][C:16]([OH:18])=O)[CH:12]=[CH:13][CH:14]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.S(Cl)([Cl:21])=O>>[C:1]([C:9]1[CH:10]=[C:11]([CH2:15][C:16]([Cl:21])=[O:18])[CH:12]=[CH:13][CH:14]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 30931(3-Benzoylphenyl)acetic acid

Product 1

HCID 15935408HCID 15935408, compound

Procedure

20 g of m-benzoyl-phenyl acetic acid (prepared by process of French patent No. 1,546,478) and 100 ml of thionyl chloride were refluxed for 3 hours and then evaporated to dryness. Excess thionyl chloride was removed by entrainment with benzene to obtain 21.74 g of m-benzoyl-phenyl-acetic acid chloride.

Workup

  1. customevaporated to dryness
  2. customExcess thionyl chloride was removed by entrainment with benzene

Sources & evidence

ORD record
ord-3854e3179d85418f831789d4fc4577a2
Source dataset
uspto-grants-1976_11
Patent number
US03995056

Reaction notes

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