N-bromobutanimide → HCID 21495672, compound

HRID 1731190Notes

Reaction equation

HRID 1731190 reaction equation
[Br:1]N1C(=O)CCC1=O.[CH3:9][O:10][C:11]1[C:25]([CH3:26])=[CH:24][CH:23]=[CH:22][C:12]=1[C:13]([C:15]1[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=1)=[O:14]>C(Cl)(Cl)(Cl)Cl.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>[CH3:9][O:10][C:11]1[C:25]([CH2:26][Br:1])=[CH:24][CH:23]=[CH:22][C:12]=1[C:13]([C:15]1[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=1)=[O:14]

Participants

5

Reactant 2

HCID 67184N-bromobutanimideHCID 21495610HCID 21495610, compound

Product 1

HCID 21495672HCID 21495672, compoundYield 98%

Reagents, catalysts & solvents 2

HCID 7187Benzoyl PeroxideCatalystHCID 5943Carbon TetrachlorideSolvent

Procedure

A mixture of 1.78 g of N-bromo-succinimide and 10 mg of benzoyl peroxide was added to a suspension of 2.6 g of 2-methoxy-3-methyl-4'-chlorobenzophenone in 15 ml of carbon tetrachloride and the solution was refluxed for 4 hours. The insolubles were removed by filtration and the filtrate was evaporated to dryness to obtain 3.32 g of 2-methoxy-3-bromomethyl-4'-chlorobenzophenone in the form of a clear yellow oil.

Workup

  1. temperaturethe solution was refluxed for 4 hours
  2. customThe insolubles were removed by filtration
  3. customthe filtrate was evaporated to dryness

Sources & evidence

ORD record
ord-eef1daab77b34bc9a1ed1a830c8ac823
Source dataset
uspto-grants-1976_11
Patent number
US03995056

Reaction notes

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