Pyridine → HCID 178448021, compound

HRID 1731282Notes

Reaction equation

HRID 1731282 reaction equation
[C:1](Cl)(=[O:3])[CH3:2].[OH:5][C:6]1[CH:11]=[CH:10][C:9]([C@H:12]2[CH2:17][CH2:16][C@H:15]([C@H:18]3[CH2:23][CH2:22][C@H:21]([CH2:24][CH2:25][CH3:26])[CH2:20][CH2:19]3)[CH2:14][CH2:13]2)=[CH:8][CH:7]=1.N1C=CC=CC=1>C1(C)C=CC=CC=1>[C:1]([O:5][C:6]1[CH:11]=[CH:10][C:9]([C@H:12]2[CH2:13][CH2:14][C@H:15]([C@H:18]3[CH2:23][CH2:22][C@H:21]([CH2:24][CH2:25][CH3:26])[CH2:20][CH2:19]3)[CH2:16][CH2:17]2)=[CH:8][CH:7]=1)(=[O:3])[CH3:2]

Participants

5

Reactant 3

HCID 1049PyridineHCID 6367Acetyl chlorideHCID 178448019HCID 178448019, compound

Product 1

HCID 178448021HCID 178448021, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

8 g of acetyl chloride is added to a solution of 30 g of trans-1-p-hydroxyphenyl-4-(trans-4-propylcyclohexyl)-cyclohexane and 20 ml of pyridine in 300 ml of toluene and the mixture is warmed to 80° for 1 hour. After cooling and customary working up, trans-1-p-acetoxyphenyl-4-(trans-4-propylcyclohexyl)-cyclohexane is obtained.

Workup

  1. temperaturethe mixture is warmed to 80° for 1 hour
  2. temperatureAfter cooling

Sources & evidence

ORD record
ord-e7b63b340f114a60800a9bfe36400126
Source dataset
uspto-grants-1986_11
Patent number
US04620938

Reaction notes

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