2,4,6-Triaminopyrimidine → HCID 13670795, compound

HRID 1731290Notes

Reaction equation

HRID 1731290 reaction equation
[CH:1](=[C:8]([C:14]([CH3:16])=O)[C:9]([O:11][CH2:12][CH3:13])=[O:10])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:17][C:18]1[N:23]=[C:22]([NH2:24])[CH:21]=[C:20]([NH2:25])[N:19]=1>C(O)(=O)C>[NH2:17][C:18]1[N:19]=[C:20]([NH2:25])[C:21]2[CH:1]([C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=3)[C:8]([C:9]([O:11][CH2:12][CH3:13])=[O:10])=[C:14]([CH3:16])[NH:24][C:22]=2[N:23]=1

Participants

4

Reactant 2

HCID 138632,4,6-TriaminopyrimidineHCID 249817Ethyl 2-benzylideneacetoacetate

Product 1

HCID 13670795HCID 13670795, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

2.2 g (10 mmol) of ethyl 2-benzylideneacetoacetate were heated under reflux for 10 hours together with 1.3 g (10 mmol) of 2,4,6-triaminopyrimidine in 25 ml of glacial acetic acid. The reaction mixture was then cooled to room temperature, and the precipitated product was filtered off with suction and recrystallized as the acetate from acetonitrile.

Workup

  1. filtrationthe precipitated product was filtered off with suction
  2. customrecrystallized as the acetate from acetonitrile

Sources & evidence

ORD record
ord-d8c744a2bb184a11aa087c4f30dec02d
Source dataset
uspto-grants-1986_11
Patent number
US04621082

Reaction notes

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