HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Amino-5-methylpyridine → 6-(3,6-Dimethylimidazo[1,2-a]pyridin-2-yl)-2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Amino-5-methylpyridine | HCID 15348 | — |
| Reactant | 6-(2-Bromopropanoyl)-2-methyl-2H-1,4-benzoxazin-3(4H)-one | HCID 20228676 | — |
| Product | 6-(3,6-Dimethylimidazo[1,2-a]pyridin-2-yl)-2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine | HCID 20228727 | 72.8% |
Reaction Steps
6-(3,6-Dimethylimidazo[1,2-a]pyridin-2-yl)-2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine (1.8 g) was prepared in substantially the same manner as that of Example 16 from 6-(2-bromopropionyl)-2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine (2.4 g) and 2-amino-5-methylpyridine (2.6 g). mp. 232° C. (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04621084 |
| Source dataset | uspto-grants-1986_11 |
| ORD ID | ord-f4306a0c20754b7990416b9da085d907 |
| Source note | uspto-grants-1986_11 |