HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminopyridine → 6-(3-Methylimidazo[1,2-a]pyridin-2-yl)-2H-1,4-benzoxazin-3(4H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminopyridine | HCID 10439 | — |
| Reactant | 6-(2-Bromopropanoyl)-2H-1,4-benzoxazin-3(4H)-one | HCID 20228669 | — |
| Product | 6-(3-Methylimidazo[1,2-a]pyridin-2-yl)-2H-1,4-benzoxazin-3(4H)-one | HCID 20228728 | 38.1% |
Reaction Steps
6-(3-Methylimidazo[1,2-a]pyridin-2-yl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazine (0.75 g) was prepared in substantially the same manner as that of Example 16 from 6-(2-bromopropionyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazine (2.0 g) and 2-aminopyridine (1.8 g). mp. 280°-282° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04621084 |
| Source dataset | uspto-grants-1986_11 |
| ORD ID | ord-87c1ebb248284dbea2b2e27743fb595e |
| Source note | uspto-grants-1986_11 |