2-Amino-3-benzyloxypyridine → HCID 20228682, compound

HRID 1731351Notes

Reaction equation

HRID 1731351 reaction equation
Br[CH:2]([CH3:15])[C:3]([C:5]1[CH:6]=[CH:7][C:8]2[O:12][C:11](=[O:13])[NH:10][C:9]=2[CH:14]=1)=O.[NH2:16][C:17]1[C:22]([O:23][CH2:24][C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)=[CH:21][CH:20]=[CH:19][N:18]=1>>[CH2:24]([O:23][C:22]1[C:17]2[N:18]([C:2]([CH3:15])=[C:3]([C:5]3[CH:6]=[CH:7][C:8]4[O:12][C:11](=[O:13])[NH:10][C:9]=4[CH:14]=3)[N:16]=2)[CH:19]=[CH:20][CH:21]=1)[C:25]1[CH:26]=[CH:27][CH:28]=[CH:29][CH:30]=1

Participants

3

Reactant 2

HCID 903342-Amino-3-benzyloxypyridineHCID 139361585-(2-Bromopropanoyl)-1,3-benzoxazol-2(3H)-one

Product 1

HCID 20228682HCID 20228682, compoundYield 27.7%

Procedure

5-(8-Benzyloxy-3-methylimidazo[1,2-a]pyridin-2-yl)-2-benzoxazolinone (0.8 g) was prepared in substantially the same manner as that of Example 30 from 5-(2-bromopropionyl)-2-benzoxazolinone (2.1 g) and 2-amino-3-benzyloxypyridine (4.8 g). mp. 264°-265° C. (dec.).

Sources & evidence

ORD record
ord-febacc9260c3467da1666d257e014e22
Source dataset
uspto-grants-1986_11
Patent number
US04621084

Reaction notes

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