Bromine → HCID 20228681, compound

HRID 1731357Notes

Reaction equation

HRID 1731357 reaction equation
[CH3:1][C:2]1[N:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]2=[N:4][C:3]=1[C:11]1[CH:16]=[CH:15][C:14]([NH:17][C:18]([NH:20][CH3:21])=[S:19])=[CH:13][CH:12]=1.BrBr>>[CH3:1][C:2]1[N:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]2=[N:4][C:3]=1[C:11]1[CH:16]=[CH:15][C:14]2[N:17]=[C:18]([NH:20][CH3:21])[S:19][C:13]=2[CH:12]=1

Participants

3

Reactant 2

HCID 24408BromineHCID 13922481HCID 13922481, compound

Product 1

HCID 20228681HCID 20228681, compoundYield 22.2%

Procedure

6-(3-Methylimidazo[1,2-a]pyridin-2-yl)-2-methylaminobenzothiazole (0.55 g) was prepared in substantially the same manner as that of Example 36 from 3-methyl-2-[4-(3-methylthioureido)phenyl]imidazo[1,2-a]pyridine (2.49 g) and bromine (1.34 g). mp. 251°-254° C. (dec.).

Sources & evidence

ORD record
ord-9bd66ee627c24825982826ae5b3b10ca
Source dataset
uspto-grants-1986_11
Patent number
US04621084

Reaction notes

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