Bromine → HCID 20228736, compound

HRID 1731358Notes

Reaction equation

HRID 1731358 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:6]([C:8]([CH3:22])=[C:9]([C:11]3[CH:16]=[CH:15][C:14]([NH:17][C:18]([NH:20][CH3:21])=[S:19])=[CH:13][CH:12]=3)[N:10]=2)[CH:7]=1.BrBr>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[N:6]([C:8]([CH3:22])=[C:9]([C:11]3[CH:12]=[CH:13][C:14]4[N:17]=[C:18]([NH:20][CH3:21])[S:19][C:15]=4[CH:16]=3)[N:10]=2)[CH:7]=1

Participants

3

Reactant 2

HCID 24408BromineHCID 13922482HCID 13922482, compound

Product 1

HCID 20228736HCID 20228736, compoundYield 38.4%

Procedure

6-(6-Chloro-3-methylimidazo[1,2-a]pyridin-2-yl)-2-methylaminobenzothiazole (1.68 g) was prepared in substantially the same manner as that of Example 36 from 6-chloro-3-methyl-2-[4-(3-methylthioureido)phenyl]imidazo[1,2-a]pyridine (4.4 g) and bromine (2.05 g).

Sources & evidence

ORD record
ord-e4193a1e3a8c4f2dbc331c6ee30c5262
Source dataset
uspto-grants-1986_11
Patent number
US04621084

Reaction notes

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