tert-Butyl chloroacetate → HCID 20228685, compound

HRID 1731366Notes

Reaction equation

HRID 1731366 reaction equation
[CH3:1][C:2]1[N:6]2[CH:7]=[CH:8][C:9]([CH3:11])=[CH:10][C:5]2=[N:4][C:3]=1[C:12]1[CH:13]=[CH:14][C:15]2[O:19][C:18](=[O:20])[NH:17][C:16]=2[CH:21]=1.Cl[CH2:23][C:24]([O:26][C:27]([CH3:30])([CH3:29])[CH3:28])=[O:25]>>[CH3:1][C:2]1[N:6]2[CH:7]=[CH:8][C:9]([CH3:11])=[CH:10][C:5]2=[N:4][C:3]=1[C:12]1[CH:13]=[CH:14][C:15]2[O:19][C:18](=[O:20])[N:17]([CH2:23][C:24]([O:26][C:27]([CH3:30])([CH3:29])[CH3:28])=[O:25])[C:16]=2[CH:21]=1

Participants

3

Reactant 2

HCID 66052tert-Butyl chloroacetateHCID 20228670HCID 20228670, compound

Product 1

HCID 20228685HCID 20228685, compoundYield 38%

Procedure

5-(3,7-Dimethylimidazo[1,2-a]pyridin-2-yl)-3-t-butoxycarbonylmethyl-2-benzoxazolinone (1.5 g) was prepared in substantially the same manner as that of Example 47 from 5-(3,7-dimethylimidazo[1,2-a]pyridin-2yl)-2-benzoxazolinone (2.8 g) and t-butyl chloroacetate (2.25 g). mp. 198°-200° C. (dec.).

Sources & evidence

ORD record
ord-a520a4d5240743b980dd539ca71a2e14
Source dataset
uspto-grants-1986_11
Patent number
US04621084

Reaction notes

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