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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1731377Generated: October 25, 2026

1-Methoxy-4-[(4-nitrophenoxy)methyl]benzene → 4-[(4-Methoxyphenyl)methoxy]aniline

https://huagongshe.com/reaction/1731377

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methoxy-4-[(4-nitrophenoxy)methyl]benzeneHCID 298745—
CatalystNickelHCID 935—
SolventTetrahydrofuran ethanolHCID 21873804—
Product4-[(4-Methoxyphenyl)methoxy]anilineHCID 13323887—

Reaction Steps

The above nitro compound was hydrogenated in THF-ethanol in the presence of Raney nickel catalyst, providing 4-[(4-methoxyphenyl)methoxy]benzenamine, mp 118°-120° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04621086
Source datasetuspto-grants-1986_11
ORD IDord-d496aaf214fd42b0a302815fb1954b6c
Source noteuspto-grants-1986_11