HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1731606Generated: October 30, 2026
Thionyl Chloride → 4-(Aminosulfonyl)-3-thiophenecarbonyl chloride
https://huagongshe.com/reaction/1731606
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 3-Thiophenecarboxylic acid, 4-(aminosulfonyl)- | HCID 3042285 | — |
| Product | 4-(Aminosulfonyl)-3-thiophenecarbonyl chloride | HCID 13732556 | — |
Reaction Steps
A solution of 1.0 g of 4-aminosulfonylthiophene-3-carboxylic acid in 20 ml of thionyl chloride is heated in an oil bath maintained at 90° C. for 2 hours. Rotoevaporation gives 1.0 g of the title compound, m.p. 236°-238° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04622402 |
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| Source dataset | uspto-grants-1986_11 |
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| ORD ID | ord-0382d7f24c91420ab51ab823e34230b9 |
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| Source note | uspto-grants-1986_11 |
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