HCID 13732639, compound → HCID 13732641, compound

HRID 1731612Notes

Reaction equation

HRID 1731612 reaction equation
[ClH:1].C([N:9]1[CH2:13][CH:12]2[CH2:14][C:15]3[C:16]([O:23][CH3:24])=[C:17]([O:21][CH3:22])[CH:18]=[CH:19][C:20]=3[CH:11]2[CH2:10]1)C1C=CC=CC=1>[Pd].CO>[ClH:1].[CH3:22][O:21][C:17]1[CH:18]=[CH:19][C:20]2[CH:11]3[CH2:10][NH:9][CH2:13][CH:12]3[CH2:14][C:15]=2[C:16]=1[O:23][CH3:24]

Participants

4

Reactant 1

HCID 13732639HCID 13732639, compound

Product 1

HCID 13732641HCID 13732641, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

4.36 g. of the resultant compound of Example 5 was hydrogenated with 0.9 g. 5% Pd/C in 100 ml. methanol at 3 atmospheres, affording 2.95 g. of product (92%), m.p. 176°-178° C.

Sources & evidence

ORD record
ord-97fc1ff7a28e4637b780698f66df4bb3
Source dataset
uspto-grants-1986_11
Patent number
US04622405

Reaction notes

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