Dichloromethane → HCID 13732643, compound

Participants

Reaction Conditions

Reaction Steps

2.00 g. of the resultant compound of Example 6 in 13 ml. CH2Cl2 under a nitrogen atmosphere at -78° C. was treated with 10 g. boron tribromide (BBr3). The mixture was stirred at 0° C. for 1 hour and then cooled to -78° C. while 50 ml. methanol was added slowly. The solution was concentrated in vacuum and the residue was crystallized from acetonitrile to get 1.97 g. product, m.p. 206°-208° C.

Provenance & Evidence