Hydrochloric Acid → HCID 70456005, compound

Participants

Reaction Conditions

Reaction Steps

A solution containing 1.4 g of the just-mentioned phenoxazine compound in 10 ml of methanol and 8 ml of acetone was treated with 10 ml of concentrated hydrochloric acid and heated to reflux for 30 minutes. The mixture was cooled to 0° C. and the solids filtered. The solid was slurried in 10 percent sodium carbonate. To this was then added 50 ml of 1:1 acetone:ethylacetate. The mixture was filtered and the layers split. The organic phase was dried over sodium sulfate and the solvent removed to give crude 3,7-diethylcarbamoyl(10H)phenoxazine.

Provenance & Evidence