Methanol → HCID 13746692, compound

Participants

Reaction Steps

A suspension of crude 2,3,10,11-tetrahydro-1H-benzo[b]indeno[5,6-f]thiepin-7-carboxylic acid (8.276 g, 28 mmole) in methanol (200 ml) containing concentrated sulfuric acid was stirred under reflux for 20 hours. The suspension was evaporated, water was added and the product was extracted with chloroform. The crude ester was purified by chromatography (250 g Merck silica gel eluted with 1:1 hexane/methylene chloride) The title compound had m.p. 110°-111° C. (from acetonitrile).

Provenance & Evidence