Phosphorus tribromide → HCID 20228215, compound

Participants

Reaction Steps

Phosphorous tribromide (0.2 ml) was added to a suspension of 3-cyano-8-hydroxymethyl-10,11-dihydrodibenzo[b,f]thiepin (500 mg; 1.87 mmole) in ether (7 ml). The reaction mixture was stirred at room temperature for one hour, then poured onto ice, extracted with ether (3×50 ml), dried over Na2SO4 and evaporated to afford 581 mg (95%) of 3-cyano-8-bromomethyl-10,11-dihydrodibenzo[b,f]thiepin as an oil.

Provenance & Evidence