HCID 13746707, compound → HCID 20228217, compound

HRID 1731632Notes

Reaction equation

HRID 1731632 reaction equation
C(C1C=CC2CCC3C=C(C[Br:18])C=CC=3SC=2C=1)#N.[C:20]([C:22]1[CH:23]=[CH:24][C:25]2[CH2:31][CH2:30][C:29]3[CH:32]=[CH:33][CH:34]=[C:35]([CH2:36]O)[C:28]=3[S:27][C:26]=2[CH:38]=1)#[N:21]>>[C:20]([C:22]1[CH:23]=[CH:24][C:25]2[CH2:31][CH2:30][C:29]3[CH:32]=[CH:33][CH:34]=[C:35]([CH2:36][Br:18])[C:28]=3[S:27][C:26]=2[CH:38]=1)#[N:21]

Participants

3

Reactant 2

HCID 13746707HCID 13746707, compoundHCID 20228215HCID 20228215, compound

Product 1

HCID 20228217HCID 20228217, compoundYield 95%

Procedure

As described previously for the 3-cyano-8-bromomethyl-10,11-dihydrodibenzo[b,f]thiepin, the title compound was prepared from 3-cyano-6-hydroxymethyl-10,11-dihydrodibenzo[b,f]thiepin in 95% yield.

Sources & evidence

ORD record
ord-8741331f01ca4954ac30e00404701575
Source dataset
uspto-grants-1986_11
Patent number
US04622403

Reaction notes

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