HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propanenitrile, 3-ethoxy- → 3-Amino-1-(5-chloro-2-pyridyl)-2-pyrazoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propanenitrile, 3-ethoxy- | HCID 16501 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | 5-Chloro-2-hydrazinylpyridine | HCID 13590464 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-Amino-1-(5-chloro-2-pyridyl)-2-pyrazoline | HCID 20228183 | — |
Reaction Steps
A 0.08 g. amount of sodium metal is dissolved in 10 ml. of absolute ethanol, then 2.5 g. of 5-chloro-2-hydrazinopyridine is added, followed by 1.70 g. of beta-ethoxypropionitrile. The procedure of Example 1 is continued to give 1.40 g. of the product of the Example as yellow crystals, m.p. 203°-204.5° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04622401 |
| Source dataset | uspto-grants-1986_11 |
| ORD ID | ord-0dd7695bf24943a1b0dc259beb62d8ac |
| Source note | uspto-grants-1986_11 |