1-(2-Nitropropoxy)-2,2,5,5-tetramethylcyclopentane → HCID 13878920, compound

HRID 1731674Notes

Reaction equation

HRID 1731674 reaction equation
[N+:1]([CH:4]([CH3:16])[CH2:5][O:6][CH:7]1[C:11]([CH3:13])([CH3:12])[CH2:10][CH2:9][C:8]1([CH3:15])[CH3:14])([O-])=O>CO.[Ni]>[NH2:1][CH:4]([CH3:16])[CH2:5][O:6][CH:7]1[C:11]([CH3:13])([CH3:12])[CH2:10][CH2:9][C:8]1([CH3:15])[CH3:14]

Participants

4

Reactant 1

HCID 138789191-(2-Nitropropoxy)-2,2,5,5-tetramethylcyclopentane

Product 1

HCID 13878920HCID 13878920, compound

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 887MethanolSolvent

Procedure

1-(2-Nitropropoxy)-2,2,5,5-tetramethylcyclopentane is dissolved in methanol and hydrogenated at 50 psi with Raney nickel T-1 as a catalyst. The reaction mixture is filtered through Celite and evaporated to yield 1-(2-aminopropoxy)-2,2,5,5-tetramethylcyclopentane.

Workup

  1. filtrationThe reaction mixture is filtered through Celite
  2. customevaporated

Sources & evidence

ORD record
ord-acf112673a704806bfbc68bbdd0ab630
Source dataset
uspto-grants-1986_11
Patent number
US04622418

Reaction notes

Loading…