3-Chloro-6-(3-chlorophenyl)-4-methylpyridazine → HCID 20226924, compound

HRID 1731718Notes

Reaction equation

HRID 1731718 reaction equation
Cl[C:2]1[N:3]=[N:4][C:5]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([Cl:15])[CH:10]=2)=[CH:6][C:7]=1[CH3:8].[H][H]>C(O)(=O)C.[Pd]>[Cl:15][C:11]1[CH:10]=[C:9]([C:5]2[N:4]=[N:3][CH:2]=[C:7]([CH3:8])[CH:6]=2)[CH:14]=[CH:13][CH:12]=1

Participants

5

Reactant 2

HCID 144502203-Chloro-6-(3-chlorophenyl)-4-methylpyridazineHCID 178418361HCID 178418361, compound

Product 1

HCID 20226924HCID 20226924, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 176Acetic AcidSolvent

Procedure

3-Chloro-6-(m-chlorophenyl)-4-methylpyridazine (7.2 g) is partially dissolved in 150 mL of acetic acid containing 1.5 g of 10% palladium on carbon. The mixture is shaken on the Parr hydrogenator until the theoretical amount of hydrogen is consumed.

Workup

  1. customis consumed

Sources & evidence

ORD record
ord-724b5ebc24564b09b55914b6fa84fe58
Source dataset
uspto-grants-1986_11
Patent number
US04623376

Reaction notes

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